Malignant neoplasms of the lymphatic system, which are characterized by damage to groups of lymph nodes and/or damage to internal organs are called lymphomas. The analysis of statistical data shows that there is incomplete information about the incidence in specific regions. The study of the prevalence of lymphomas, the need to monitor the incidence, and the identification and analysis of possible links between pathology and urban environmental features are an urgent problem. The paper analyzes the dynamics of the incidence of non-Hodgkin’s lymphoma in Saratov from 2009 to 2019.